The appendix is a blind ending, curved crest attached to the early part of the colon (cecum). On its inner surface it is covered with cells that emit a sparing amount of slime secretion that drains to the cecum. The wall of the appendix contains mostly muscle and lymphatic tissue. The latter is part of the immune system of the body and involved in the production of antibodies. Appendicitis symptoms are usually considered with severe abdominal pain.
Appendicitis is an inflammation of the appendix. It occurs as a result of blocking the runoff of the appendix, most often with the accumulation of thick mucus secretions, from faecal masses that have entered the cecum or the growth of the lymph tissue. This creates conditions for bacteria that normally live and develop in the appendicitis to penetrate the wall and to provoke the development of an inflammatory process.
When the inflammation progresses, it may also affect the peritoneum, as well as tearing the appendix to pour its contents into the free abdominal cavity. In the USA, acute appendicitis develops 1 out of every 500 people per year. Globally, the disease affects 6% of the population. It is particularly common between 10 and 30 years of age. Increased attention is desirable in the elderly because of the increased risk of complications.
Most common appendicitis symptoms are sudden severe abdominal pain, which usually occurs at night or in the morning. At first it is rather diffuse and weakly localized. It gradually becomes more intense and focuses in the lower right quarter of the abdomen. The detection of pain at the indicated site is indicative of the spread of the inflammatory process to the peritoneum. Also appendicitis symptoms include acute nausea and vomiting occurred, fever (increase in body temperature), a disturbance in the functioning of the digestive tract, which may occur in the form of constipation (constipation) and retention of gas or vice versa in the form of diarrhea.